Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood–derived mesenchymal stem cells combined with hyaluronate hydrogel composite

Bo Seung Bae ¹, Jae Woong Jung ¹, Gyeong Ok Jo ¹, Seon Ae Kim ¹, Eun Jeong Go ¹, Mi-La Cho ², Asode Ananthram Shetty ³ and Seok Jung Kim ^1,4

¹ Department of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
² The Rheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
³ Institute of Medical Sciences, Faculty of Health and Social Care, Canterbury Christ Church University, Canterbury, UK
⁴ Department of Orthopedic Surgery, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea

게재지 <Stem Cell Research & Therapy>

Anterior-to-Central Cartilage Defects of Arthritic Knee Showed Better Cartilage Regeneration Than Posterior Cartilage Defects Using Mesenchymal Stem Cell Implantation

Se-Han Jung ¹, Hong Seon Lee ², Min Jung ¹, Kwangho Chung ³, Sungjun Kim ², Jeehoon Choi ⁴, Chong Hyuk Choi ¹, Sung-Hwan Kim ⁵

¹ Arthroscopy and Joint Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Orthopedic Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
² Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
³ Arthroscopy and Joint Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Orthopedic Surgery, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
⁴ Department of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
⁵ Arthroscopy and Joint Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

게재지 <Arthroscopy: The Journal of Arthroscopic and Related Surgery>

Transplantable stem cell nanobridge scaffolds for accelerating articular cartilage regeneration

Sunho Park ^a,b,c, Ju Yong Na ^d, Yonghyun Gwon ^a,b,c, Woochan Kim ^a,b,c, Ju Yeon Kang ^d, Jong Keun Seon ^d, Jangho Kim ^a,b,c,e

^a Department of Convergence Biosystems Engineering, Chonnam National University, Gwangju, 61186, Republic of Korea
^b Department of Rural and Biosystems Engineering, Chonnam National University, Gwangju, 61186, Republic of Korea
^c Interdisciplinary Program in IT-Bio Convergence System, Chonnam National University, Gwangju 61186, Republic of Korea
^d Department of Orthopedics, Chonnam National University Medical School & Hospital, Hwasun 58128, Republic of Korea
^e Institute of Nano-Stem Cells Therapeutics, NANOBIOSYSTEM Co., Ltd, Gwangju, Republic of Korea

게재지 <Biomaterials>

Fabrication of atelocollagen-coated bioabsorbable suture and the evaluation of its regenerative efficacy in Achilles tendon
healing using a rat experimental model

Yong Ho Yeo ^a, Seong Kyeong Jo ^b, Min Hee Kim ^c, Su Jeong Lee ^d, Seung Yun Han ^e, Mun Hyang Park ^f, Dae Young Kim ^f, Dae Yeung Kim ^b, In Ha Yoo ^g, Chan Kang ^h,
Jae Hwang Song ^b, Won Ho Park ^a

^a Department of Organic Materials Engineering, Chungnam National University, Daejeon, Republic of Korea
^b Department of Orthopedic Surgery, Konyang University Hospital, Daejeon, Republic of Korea
^c Department of Textile Engineering, Kyungpook National University, Republic of Korea
^d R&D planning team, Organoid Sciences Co., Ltd., 331, Pangyo-ro, Bundang-gu, Seongnam-si, Republic of Korea
^e Department of Anatomy, College of Medicine, Konyang University, Daejeon, Republic of Korea
^f Department of Pathology, College of Medicine, Konyang University, Daejeon, Republic of Korea
^g Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul

게재지 <International Journal of Biological Macromolecules>

Promoting angiogenesis and diabetic wound healing through delivery of protein transduction domain-BMP2 formulated
nanoparticles with hydrogel

Jae Wan Suh ¹ , Kyoung-Mi Lee ², Eun Ae Ko ², Dong Suk Yoon ³, Kwang Hwan Park ² , Hyun Sil Kim ⁴, Jong In Yook ⁴, Nam Hee Kim ⁴, Jin Woo Lee ^2,5

¹ Department of Orthopaedic Surgery, Dankook University College of Medicine, Cheonan, South Korea
² Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, South Korea
³ Department of Biomedical Science, Hwasung Medi-Science University, Hwaseong-Si, Gyeonggi-Do, South Korea
⁴ Department of Oral Pathology, Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, South Korea
⁵ Brain Korea 21 PLUS Project for Medical

게재지 <Journal of Tissue Engineering>

Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients
With Knee Osteoarthritis?
A Systematic Review With Meta-analysis of Randomized Controlled Trials

Kang-Il Kim ^1,2, Myung-Seo Kim ¹, Jun-Ho Kim ¹

¹ Department of Orthopaedic Surgery, Center for Joint Diseases, Kyung Hee University Hospital at Gangdong
² Department of Orthopaedic Surgery, School of Medicine, Kyung Hee University, Seoul, Republic of Korea

게재지 <The American Journal of Sports Medicine>

Three-dimensional printed polylactic acid scaffold integrated with BMP-2 laden hydrogel for precise bone regeneration

Misun Cha ^1,2, Yuan-Zhe Jin ^3,4,5, Jin Wook Park ¹, Kyung Mee Lee ², Shi Huan Han ³, Byung Sun Choi ², Jae Hyup Lee ^6,7,8

¹ Biotechnology Institute, Medifab Co. LTD., 70, Dusan-ro, Doksan-dong, Geumcheon-gu
² Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center
³ Department of Orthopedic Surgery, College of Medicine, Seoul National University
⁴ Spine Department, The First Hospital of Jilin University, China
⁵ Jilin Engineering Research Center for Spine and Spinal Cord Injury China
⁶ Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center
⁷ Department of Orthopedic Surgery, College of Medicine, Seoul National University
⁸ Institute of Medical and Biological Engineering, Seoul National University Medical Research Center

게재지 <Biomaterials Research>

Fabrication of decellularized meniscus extracellular matrix according to inner cartilaginous, middle transitional, and outer
fibrous zones result in zone-specific protein expression useful for precise replication of meniscus zones

Hee-Woong Yun ^a,b, Bo Ram Song ^b, Dong Il Shin ^b,c, Xiang Yun Yin ^a,b, Minh-Dung Truong ^b, Sujin Noh ^d, Young Jun Jin ^a,b, Hyeon Jae Kwon ^b,c, Byoung-Hyun Min ^a,b,c,
Do Young Park ^a,b

^a Department of Orthopedic Surgery, School of Medicine, Ajou University, Suwon, Republic of Korea
^b Cell Therapy Center, Ajou Medical Center, Suwon, Republic of Korea
^c Department of Molecular Science and Technology, Ajou University, Suwon, Republic of Korea
^d Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Republic of Korea

게재지 <Materials Science & Engineering C>

Clinical Efficacy of Platelet Rich Plasma Injection and Its Association With Growth Factors in the Treatment of Mild to Moderate 
Knee Osteoarthritis: A Randomized Double Blind Controlled Clinical Trial As Compared With Hyaluronic Acid

Yong-Beom Park ¹, Jun-Ho Kim ², Chul-Won Ha ^3,4,5, Dong-Hyun Lee ⁶

¹ Department of Orthopedic Surgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea
² Department of Orthopedic Surgery, Seoul Medical Center, Seoul, Republic of Korea
³ Department of Orthopedic Surgery, Samsung Medical Center, Seoul, Republic of Korea
⁴ Stem Cell and Regenerative Medicine Institute, Samsung Medical Center, Seoul, Republic of Korea
⁵ Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea
⁶ Department of Orthopedic Surgery, Himchan Hospital

게재지 <The American Journal of Sports Medicine>

Development of stabilized dual growth factor-loaded hyaluronate collagen dressing matrix

Jihyun Kim ^1,2, Kyoung-Mi Lee ^1,3, Seung Hwan Han ⁴, Eun Ae Ko ¹, Dong Suk Yoon ¹, Ik Kyu Park ⁵, Hang-Cheol Shin ⁶,
Kwang Hwan Park ¹, Jin Woo Lee ^1,2,3

¹ Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, South Korea
² Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, South Korea
³ Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, South Korea
⁴ Department of Orthopaedic Surgery, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, South Korea
⁵ R&D Center, Genewel Co., Ltd., Sungnam, South Korea
⁶ School of Systems Biomedical Science, Soongsil University, Seoul, South Korea

게재지 <Journal of Tissue Engineerin>